Dixie Chicks Kick Off Tour With Donald Trump in the Backdrop

The Dixie Chicks aren't afraid of mixing art and politics.

The Texas-based trio kicked off their DCX MMXVI World Tour on on Wednesday in Cincinnati and they've got a new political foe: Donald Trump.

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The Dixie Chicks performed their 1999 hit "Goodbye Earl" against a backdrop that showed Trump with devil horns and a comical mustache and goatee.

Natalie Maines is no stranger to political controversy. In 2003, she slammed George W. Bush for his plans to invade Iraq.

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Maines also took aim at Trump back in January with with a seemingly playful tweet:

Natalie Maines

As long as Donald Trump's decisions for America are as solid as his decision about his hair, we're in good shape.

11:39 AM - Jan 24, 2016
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She expressed her grievances with his former Republican primary opponent, Ted Cruz, tweeting:

Natalie Maines

Just so you know....I'm ashamed Ted Cruz is from America;)

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11:20 AM - Jan 24, 2016
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When Maines learned of Cruz's naturalized citizenship (he was actually born in Canada), she followed up:

Natalie Maines

I stand corrected...Just so you know, I'm ashamed Ted Cruz claims to be American. pic.twitter.com/JUltNImOXH

11:56 AM - Jan 24, 2016
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Maines is well aware that her political commentary can have ramifications. Ten years after her infamous Bush comments in 2003, the singer told Rolling Stone, "I joke that I have PTSD, but there's probably truth in that joke."

But she doesn't regret speaking out in the first place.

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"It all put an ugly light on people that I was kind of happily naive to," she said. "But when I was going through it, I really didn't feel like it was affecting me. I was in fight mode and battle mode, and I felt, you know, I was right, and free to say what I want to say."